Quick answers
Who counters Seraphine in Wild Rift?
In the matchup data documented in Rift Lab, these are the harder matchups for Seraphine: Blitzcrank (Support), Pyke (Support), Leona (Support), Nautilus (Support), Brand (Mid). This is a documented matchup list, not a win rate: TheNexus does not publish win-rate or pick-rate figures it cannot source.
How do you play against Seraphine in Wild Rift?
Riot's ability text for Seraphine describes crowd control (a stun, root, knock-up, pull or similar) in BEAT DROP (ability 3); a shield in SURROUND SOUND (ability 2). Plan around those abilities before a trade or a fight. These notes are keyword matches over the ability text only, not a rating of how strong Seraphine is, so read the full descriptions on this page.
What is the best build for Seraphine in Wild Rift?
The Nexus-reviewed core build for Seraphine, in purchase order: Luden's Echo then Cryptbloom then Rabadon's Deathcap then Boots of Mana. Runes: Aery, Font of Life, Bone Plating, Revitalize, Transcendence. Situational swaps: against enemy crowd control: Banshee's Veil; against enemy shields: Oceanid's Trident. This is a reviewed snapshot (patch 7.2b), not a build ranked by win rate.
Which lane and role does Seraphine play in Wild Rift?
Seraphine is a Mage and Support by Riot's classification and is played in Support. Riot rates the difficulty Low. On our tier-list snapshot (patch 7.2b) it shows A tier from its external source, which is a snapshot letter and not a TheNexus win rate.
Every answer here is built from Rift Lab data and Riot's own ability text. Where the data is missing we say so instead of guessing.