Quick answers
Who counters Karma in Wild Rift?
In the matchup data documented in Rift Lab, these are the harder matchups for Karma: Blitzcrank (Support), Pyke (Support), Nautilus (Support), Leona (Support), Brand (Mid). This is a documented matchup list, not a win rate: TheNexus does not publish win-rate or pick-rate figures it cannot source.
How do you play against Karma in Wild Rift?
Riot's ability text for Karma describes crowd control (a stun, root, knock-up, pull or similar) in FOCUSED RESOLVE (ability 2), TRANSCENDENT EMBRACE (ultimate); a shield in INSPIRE (ability 3). Plan around those abilities before a trade or a fight. These notes are keyword matches over the ability text only, not a rating of how strong Karma is, so read the full descriptions on this page.
What is the best build for Karma in Wild Rift?
The Nexus-reviewed core build for Karma, in purchase order: Imperial Mandate then Ardent Censer then Redemption then Ionian Boots of Lucidity. Runes: Arcane Comet, Manaflow Band, Transcendence, Scorch, Bone Plating. Situational swaps: against enemy crowd control: Mikael's Blessing; against enemy shields: Oceanid's Trident; against enemy healing: Morellonomicon. This is a reviewed snapshot (patch 7.2b), not a build ranked by win rate.
Which lane and role does Karma play in Wild Rift?
Karma is a Mage and Support by Riot's classification and is played in Support. Riot rates the difficulty High. On our tier-list snapshot (patch 7.2b) it shows A tier from its external source, which is a snapshot letter and not a TheNexus win rate.
Every answer here is built from Rift Lab data and Riot's own ability text. Where the data is missing we say so instead of guessing.