Quick answers
Who counters Ryze in Wild Rift?
In the matchup data documented in Rift Lab, these are the harder matchups for Ryze: Zed (Mid), Fizz (Mid), Yasuo (Mid), Kassadin (Mid), Talon (Jungle). This is a documented matchup list, not a win rate: TheNexus does not publish win-rate or pick-rate figures it cannot source.
How do you play against Ryze in Wild Rift?
Riot's ability text for Ryze describes crowd control (a stun, root, knock-up, pull or similar) in RUNE PRISON (ability 2); a dash, leap or blink in OVERLOAD (ability 1). Plan around those abilities before a trade or a fight. These notes are keyword matches over the ability text only, not a rating of how strong Ryze is, so read the full descriptions on this page.
What is the best build for Ryze in Wild Rift?
The Nexus-reviewed core build for Ryze, in purchase order: Rod of Ages then Archangel's Staff then Rabadon's Deathcap then Boots of Mana. Runes: Phase Rush, Manaflow Band, Transcendence, Nimbus Cloak, Bone Plating. Situational swaps: against enemy shields: Oceanid's Trident; against enemy crowd control: Banshee's Veil; against enemy front line: Cut Down. This is a reviewed snapshot (patch 7.2b), not a build ranked by win rate.
Which lane and role does Ryze play in Wild Rift?
Ryze is a Mage by Riot's classification and is played in Mid. Riot rates the difficulty Medium. On our tier-list snapshot (patch 7.2b) it shows S+ tier from its external source, which is a snapshot letter and not a TheNexus win rate.
Every answer here is built from Rift Lab data and Riot's own ability text. Where the data is missing we say so instead of guessing.