Vayne counters and synergies

Matchup page

In-game title: the Night Hunter
Lane: Dragon / ADC
Source tier: S

8picks that punish it
5picks that work with it
18pages name it as their answer

Harder matchups for this pick

Caitlynthe Sheriff of PiltoverDragon / ADC21B
Draventhe Glorious ExecutionerDragon / ADC18A
Ashethe Frost ArcherDragon / ADC10A
MalphiteShard of the MonolithBaron / Top19S
Vithe Piltover EnforcerJungle21S
Pantheonthe Unbreakable SpearJungle14S
Nautilusthe Titan of the DepthsSupport35A
Lee Sinthe Blind MonkJungle28A

Useful alongside this pick

Luluthe Fae SorceressSupport14S
MilioTHE GENTLE FLAMESupport1S
Jannathe Storm's FurySupport20B
Namithe TidecallerSupportS
Braumthe Heart of the FreljordSupport18S

Champion pages that name this pick as their answer

AatroxThe Darkin BladeBaron / Top1S
Dariusthe Hand of NoxusBaron / TopA
Dr. Mundothe Madman of ZaunBaron / TopB
Ezrealthe Prodigal ExplorerDragon / ADC1S+
Garenthe Might of DemaciaBaron / Top1A
GwenThe Hallowed SeamstressBaron / Top20S
K'SantéThe Pride of NazumahBaron / TopS
MalphiteShard of the MonolithBaron / Top19S
MordekaiserTHE IRON REVENANTBaron / Top4A
Nasusthe Curator of the SandsBaron / TopA
OrnnThe Fire Below The MountainBaron / Top1S
PoppyKEEPER OF THE HAMMERBaron / Top6S
Settthe BossBaron / Top6A
Shenthe Eye of TwilightBaron / Top1S
Singedthe Mad ChemistBaron / TopA
Sionthe Undead JuggernautBaron / Top1B
UrgotTHE DREADNOUGHTBaron / TopB
VolibearThe Relentless StormBaron / TopS

Matchup tips: picks that punish it

Caitlyn

Dragon / ADC is also this pick's lane, so the two meet head-on in lane.
This pick's 2 Silver Bolts shields or heals, and the reviewed build for this counter keeps Mortal Reminder as its answer to that.
The reviewed build opens with: The Collector
The reviewed rune page includes: Lethal Tempo

Draven

Dragon / ADC is also this pick's lane, so the two meet head-on in lane.
This pick's 2 Silver Bolts shields or heals, and the reviewed build for this counter keeps Lord Dominik's Regards as its answer to that.
The reviewed build opens with: Bloodthirster
The reviewed rune page includes: Conqueror

Ashe

Dragon / ADC is also this pick's lane, so the two meet head-on in lane.
This pick's 2 Silver Bolts shields or heals, and the reviewed build for this counter keeps Mortal Reminder as its answer to that.
The reviewed build opens with: Kraken Slayer
The reviewed rune page includes: Lethal Tempo

Malphite

Usually met from Baron / Top while this pick plays Dragon / ADC so the matchup is decided in rotations and team fights more than in lane.
This pick's 2 Silver Bolts shields or heals, so trade while it is on cooldown.
The reviewed build opens with: Zeke's Convergence
The reviewed rune page includes: Grasp of the Undying

Vi

Usually met from Jungle while this pick plays Dragon / ADC so the matchup is decided in rotations and team fights more than in lane.
This pick's 2 Silver Bolts shields or heals, and the reviewed build for this counter keeps Mortal Reminder as its answer to that.
The reviewed build opens with: Trinity Force
The reviewed rune page includes: Conqueror

Pantheon

Usually met from Jungle while this pick plays Dragon / ADC so the matchup is decided in rotations and team fights more than in lane.
This pick's 2 Silver Bolts shields or heals, and the reviewed build for this counter keeps Mortal Reminder as its answer to that.
The reviewed build opens with: Serpent's Fang
The reviewed rune page includes: First Strike

Nautilus

Usually met from Support while this pick plays Dragon / ADC so the matchup is decided in rotations and team fights more than in lane.
This pick's 2 Silver Bolts shields or heals, and the reviewed build for this counter keeps Thornmail as its answer to that.
The reviewed build opens with: Warmog's Armor
The reviewed rune page includes: Ice Overlord

Lee Sin

Usually met from Jungle while this pick plays Dragon / ADC so the matchup is decided in rotations and team fights more than in lane.
This pick's 2 Silver Bolts shields or heals, so trade while it is on cooldown.
The reviewed build opens with: Youmuu's Ghostblade
The reviewed rune page includes: Conqueror

Matchup tips: picks that work with it

Lulu

Plays Support next to this pick's Dragon / ADC so the two can coordinate lane pressure and objective timing.
3 Condemn is crowd control and 3 HELP, PIX! is a dash or blink: control first, then close the gap.
This pick has no shield of its own, and 3 HELP, PIX! supplies one.
The reviewed build opens with: Ardent Censer

Milio

Plays Support next to this pick's Dragon / ADC so the two can coordinate lane pressure and objective timing.
3 Condemn and 1 ULTRA MEGA FIRE KICK are both crowd control in Riot's text, so chain them instead of casting them together.
This pick has no shield of its own, and 3 WARM HUGS supplies one.
The reviewed build opens with: Harmonic Echo

Janna

Plays Support next to this pick's Dragon / ADC so the two can coordinate lane pressure and objective timing.
This pick has no shield of its own, and 3 Eye Of The Storm supplies one.
The reviewed build opens with: Harmonic Echo
The reviewed rune page includes: Aery

Nami

Plays Support next to this pick's Dragon / ADC so the two can coordinate lane pressure and objective timing.
3 Condemn and 1 Aqua Prison are both crowd control in Riot's text, so chain them instead of casting them together.
The reviewed build opens with: Ardent Censer
The reviewed rune page includes: Aery

Braum

Plays Support next to this pick's Dragon / ADC so the two can coordinate lane pressure and objective timing.
3 Condemn is crowd control and 2 Stand Behind Me is a dash or blink: control first, then close the gap.
This pick has no shield of its own, and 1 Winter's Bite supplies one.
The reviewed build opens with: Knight's Vow

Kit notes are keyword matches over Riot's ability text and the reviewed builds of both champions. They are guidance, not win rates.

Open the full champion guide: abilities, build and runes

Every count on this page is a count of documented links, not a win rate or a strength score.

Quick answers

Who counters Vayne in Wild Rift?

In the matchup data documented in Rift Lab, these are the harder matchups for Vayne: Caitlyn (Dragon / ADC), Draven (Dragon / ADC), Ashe (Dragon / ADC), Malphite (Baron / Top), Vi (Jungle), Pantheon (Jungle), Nautilus (Support), Lee Sin (Jungle). This is a documented matchup list, not a win rate: TheNexus does not publish win-rate or pick-rate figures it cannot source.

How do you play against Vayne in Wild Rift?

Riot's ability text for Vayne describes crowd control (a stun, root, knock-up, pull or similar) in Condemn (ability 3); healing or regeneration in Silver Bolts (ability 2). Plan around those abilities before a trade or a fight. These notes are keyword matches over the ability text only, not a rating of how strong Vayne is, so read the full descriptions on this page.

What is the best build for Vayne in Wild Rift?

The Nexus-reviewed core build for Vayne, in purchase order: Blade of the Ruined King then Guinsoo's Rageblade then Magnetic Blaster then Berserker's Greaves. Runes: Lethal Tempo, Brutal, Cut Down, Legend: Bloodline, Bone Plating. Situational swaps: against enemy crowd control: Mercurial Scimitar. This is a reviewed snapshot (patch 7.2b), not a build ranked by win rate.

Which lane and role does Vayne play in Wild Rift?

Vayne is a Marksman and Assassin by Riot's classification and is played in Dragon / ADC. Riot rates the difficulty Medium. On our tier-list snapshot (patch 7.2b) it shows S tier from its external source, which is a snapshot letter and not a TheNexus win rate.

Every answer here is built from Rift Lab data and Riot's own ability text. Where the data is missing we say so instead of guessing.